Chronic Lymphocytic Leukemia
Purpose
Chronic lymphocytic leukemia (CLL) is the most common form of leukemia in the Western world. Although targeted therapies have improved outcomes, these treatments are not curative. Long-term use is associated with resistance, toxicity, and high costs. Computed tomography (CT) is currently the standard imaging technique to assess treatment response. However, a CT scan without enlarged lymph nodes does not rule out residual disease, and enlarged nodes may persist without the presence of active disease. Advanced quantitative imaging (radiomics) and new imaging techniques such as positron emission tomography (PET/CT) may offer better insights into treatment response.
Objectives
To identify potential prognostically relevant image characteristics for CLL patients
